Detalhe da pesquisa
1.
A Phase I dose-escalation study of two cycles carboplatin-olaparib followed by olaparib monotherapy in patients with advanced cancer.
Int J Cancer
; 148(12): 3041-3050, 2021 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33539540
2.
Phase I Study of Afatinib and Selumetinib in Patients with KRAS-Mutated Colorectal, Non-Small Cell Lung, and Pancreatic Cancer.
Oncologist
; 26(4): 290-e545, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33296125
3.
Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.
Pharmacogenomics J
; 21(3): 336-345, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33649517
4.
Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer.
Br J Cancer
; 122(8): 1166-1174, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32147669
5.
Quantification of the pharmacokinetic-toxicodynamic relationship of oral docetaxel co-administered with ritonavir.
Invest New Drugs
; 38(5): 1526-1532, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32306204
6.
Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).
Invest New Drugs
; 38(4): 1117-1128, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31667659
7.
Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).
Invest New Drugs
; 38(4): 1096-1107, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31637669
8.
Phase I pharmacological study of continuous chronomodulated capecitabine treatment.
Pharm Res
; 37(5): 89, 2020 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32382808
9.
Mitochondria of a human multidrug-resistant hepatocellular carcinoma cell line constitutively express inducible nitric oxide synthase in the inner membrane.
J Cell Mol Med
; 19(6): 1410-7, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25691007
10.
Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer.
Br J Cancer
; 113(3): 396-402, 2015 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-26180927
11.
"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".
Invest New Drugs
; 32(6): 1083-95, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25078948
12.
Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.
Invest New Drugs
; 31(5): 1125-35, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23315030
13.
Pharmacokinetics of eribulin mesylate in patients with solid tumours receiving repeated oral rifampicin.
Br J Clin Pharmacol
; 75(2): 507-15, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22803519
14.
The effect of Echinacea purpurea on the pharmacokinetics of docetaxel.
Br J Clin Pharmacol
; 76(3): 467-74, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23701184
15.
Pharmacokinetics and Toxicities of Oral Docetaxel Formulations Co-Administered with Ritonavir in Phase I Trials.
Clin Pharmacol
; 13: 21-32, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33536797
16.
Population Pharmacokinetics of Intracellular 5-Fluorouridine 5'-Triphosphate and its Relationship with Hand-and-Foot Syndrome in Patients Treated with Capecitabine.
AAPS J
; 23(1): 23, 2021 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33417061
17.
Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours.
Drugs R D
; 21(1): 103-111, 2021 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-33464545
18.
Transtympanic Sodium Thiosulfate for Prevention of Cisplatin-Induced Ototoxicity: A Randomized Clinical Trial.
Otol Neurotol
; 42(5): 678-685, 2021 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33710154
19.
A Phase 1 Dose-Escalation Study of Low-Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors.
Clin Pharmacol Drug Dev
; 10(6): 607-621, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33021083
20.
No relation between docetaxel administration route and high-grade diarrhea incidence.
Pharmacol Res Perspect
; 8(4): e00633, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32725720